A heterobimetallic tetrahedron from a linear platinum(II)-bis(acetylide) metalloligand

• Matthias Hardy,
• Marianne Engeser and
• Arne Lützen

Beilstein J. Org. Chem. 2020, 16, 2701–2708, doi:10.3762/bjoc.16.220

• diastereomers. The new complexes were characterized by NMR and UV–vis spectroscopy and ESI mass spectrometry. Using GFN2-xTB we generated energy-minimized models of the diastereomers of this cage that further corroborated the results from analytical findings. Keywords: cage compounds; heterobimetallic

• complexes; pyridylimine ligands; self-assembly; supramolecular chemistry; Introduction The understanding of the general design principles for the self-assembly of metallosupramolecular aggregates [1][2][3][4][5] allowed to access more and more complex and large assemblies over the past decades like

Easy access to heterobimetallic complexes for medical imaging applications via microwave-enhanced cycloaddition

• Nicolas Desbois,
• Sandrine Pacquelet,
• Adrien Dubois,
• Clément Michelin and
• Claude P. Gros

Beilstein J. Org. Chem. 2015, 11, 2202–2208, doi:10.3762/bjoc.11.239

• ” reaction, has been applied to the synthesis of a range of triazole-linked porphyrin/corrole to DOTA/NOTA derivatives. Microwave irradiation significantly accelerates the reaction. The synthesis of heterobimetallic complexes was easily achieved in up to 60% isolated yield. Heterobimetallic complexes were

• lead to a ‘marriage of convenience’ [1]. Our group previously reported the synthesis of porphyrin-DOTA-like scaffolds for multimodal imaging [2][3]. We were interested in heterobimetallic complexes incorporating both gadolinium and copper atoms. We now want to report new multimodal porphyrinoids-DOTA

• -like macrocycle on the other side, have been easily linked by microwave azide–alkyne 1,3-dipolar cycloaddition. The preliminary relaxivity study of these heterobimetallic complexes was also investigated for potential MRI applications. Results and Discussion We first wish to report a “library” of azido